INTEGRATIVE ANALYSIS OF BULK AND SINGLE-CELL RNA-SEQ REVEALS THE MOLECULAR CHARACTERIZATION OF THE IMMUNE MICROENVIRONMENT AND OXIDATIVE STRESS SIGNATURE IN MELANOMA

Background: The immune microenvironment and oxidative stress of melanoma show significant heterogeneity, which affects tumor growth, invasion and treatment response.Single-cell and bulk RNA-seq data were used to explore the heterogeneity of the immune microenvironment and oxidative stress of melanoma.Methods: The R package Seurat facilitated the an

In context of the Kids Footwear Corona pandemic, telemedicine acquired a new significance.Whereas previously the aim was to override given barriers, now, in the case of a pandemic, the main idea is to create an intentional distance between patients and healthcare professionals in order to avoid cross-infection.To meet the needs of a fully diagnosti

Artificial ponds or irrigated systems scattered throughout farmlands can offer important habitats for anurans and can be interesting sites for research on species resources use in a changing landscape.This study describes the diet Teethers and resource partitioning among anurans inhabiting irrigated rice fields in the Pantanal region.Twenty categor